Human IL-18 Recombinant Protein

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SKU:
PC-H-IL18-100UG
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The Human IL-18 Recombinant protein is a premium-grade product derived from the gene responsible for encoding a potent proinflammatory cytokine. This cytokine has the capacity to stimulate IFN-gamma production in T cells, crucial for the immune response. Furthermore, in conjunction with IL12, it has been observed to inhibit the generation of IL4-dependent IgE and IgG1 by B cells while simultaneously boosting IgG2a production, an essential immunoglobulin.

To ensure optimal functionality, our Human IL-18 Recombinant protein is combined with IL-18 binding protein. This component can selectively interact with the cytokine, modulating its biological activity as needed.

Product Specifications
 
Species Human
Expression System E. coli
Amino acid sequence YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIIS MYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDII FFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIM FTVQNED
Molecular weight 18 kDa
Class Recombinant
Type Protein
Purity >95% by SDS-PAGE
Endotoxin concentration <1 EU/µg
Activity
Determined by the dose-dependent production of IFN-gamma by human KG-1 myelomonocyte cells.
Conjugate Unconjugated
Form Lyophilized
Contains no preservative
Storage Conditions  -20°C

 

CAUTION

For Research Use Only. Not for use in diagnostic procedures.