Products - Page 1 - Pacific Coast Biologics

Human VEGF 165 Recombinant Protein

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Human KGF Recombinant Protein

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Human IL-11 Recombinant Protein

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Human IL-5 Recombinant Protein

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Human basic FGF 146 (a.a.) Recombinant Protein

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Human IGF-LR3 Recombinant Protein

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Human IGF-2 Recombinant Protein

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Human Activin A Recombinant Protein

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Human PDGF-AA Recombinant Protein

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Human beta-NGF Recombinant Protein

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Human Heregulin beta-1 Recombinant Protein

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Human CNTF Recombinant Protein

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Human GDNF Recombinant Protein

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Human BDNF Recombinant Protein

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Human NT-4 Recombinant Protein

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Human NT-3 Recombinant Protein

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Human G-CSF Recombinant Protein

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Human GM-CSF Recombinant Protein

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Human M-CSF Recombinant Protein

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Human IFN gamma Recombinant Protein

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Human TNF alpha Recombinant Protein

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Human IL-21 Recombinant Protein

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Human IL-15 Recombinant Protein

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Human IL-10 Recombinant Protein

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Human VEGF 165 Recombinant Protein

VEGF stands out as a potent cytokine, driving growth and angiogenesis. It fosters endothelial cell proliferation and survival, contributing significantly to angiogenesis and vascular permeability. Its expression in vascularized tissues plays a crucial...

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Human KGF Recombinant Protein

KGF, also known as FGF-7, belongs to the FGF family, which comprises 23 known members. This family of proteins plays a pivotal role in prenatal development, postnatal growth, and tissue regeneration by promoting cellular proliferation and differentiation...

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Human IL-11 Recombinant Protein

IL-11, a versatile cytokine, originates from stromal cells like fibroblasts, epithelial cells, and osteoclasts. Its expression spans across various tissues, including the thymus, lungs, bones, connective tissues, and the central nervous system...

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Human IL-5 Recombinant Protein

IL-5 functions as a growth factor in hematopoiesis, fostering the proliferation and activation of eosinophils. Its production primarily stems from mast cells, T cells, and eosinophils themselves. IL-5 plays a pivotal role in bolstering cell-mediated...

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Human basic FGF 146 (a.a.) Recombinant Protein

FGF-basic stands as one of the 23 recognized members within the FGF family. These proteins hold pivotal roles in prenatal development, postnatal growth, and tissue regeneration by fostering cellular proliferation and differentiation. FGF-basic,...

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Human IGF-LR3 Recombinant Protein

The IGFs, or insulin-like growth factors, are polypeptide growth factors known for their ability to stimulate the proliferation and survival of various cell types, including those found in muscle, bone, and cartilage tissue when studied in vitro. While...

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Human IGF-2 Recombinant Protein

IGFs, or insulin-like growth factors, are polypeptide growth factors known for their ability to stimulate the proliferation and survival of various cell types, including those found in muscle, bone, and cartilage tissue when studied in vitro. They are...

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Human Activin A Recombinant Protein

Activin A, a member of the TGF-β family, showcases diverse biological functions, including the regulation of cellular proliferation and differentiation, as well as the promotion of neuronal survival. Its elevated presence in colorectal tumors in...

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Human PDGF-AA Recombinant Protein

PDGFs exist as disulfide-linked dimers comprising two polypeptide chains, PDGF-A and PDGF-B, each weighing between 12.0 and 13.5 kDa. Among the three naturally occurring PDGFs—PDGF-AA, PDGF-BB, and PDGF-AB—all are potent mitogens affecting...

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Human beta-NGF Recombinant Protein

β-NGF, a neurotrophic factor structurally akin to BDNF, NT-3, and NT-4, is part of the cysteine-knot family of growth factors, characterized by stable dimeric structures. This potent neurotrophic factor operates via its receptor β-NGFR, playing...

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Human Heregulin beta-1 Recombinant Protein

Neuregulin/Heregulin represents a group of closely related polypeptide growth factors generated from alternate gene splicing (NRG1, NRG2, NRG3, and NRG4). Currently, there are more than 14 soluble and membrane-bound proteins derived from the NRG1 gene...

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Human CNTF Recombinant Protein

CNTF, initially identified as crucial for the survival of chick ciliary neurons in lab cultures, plays a significant role in supporting various neural cell types' survival. These include primary sensory neurons, motor neurons, basal forebrain...

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Human GDNF Recombinant Protein

GDNF is a homodimeric neurotrophic factor connected by disulfide bonds, sharing structural similarities with Artemin, Neurturin, and Persephin. These proteins are part of the cysteine-knot superfamily of growth factors, known for their stable dimeric...

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Human BDNF Recombinant Protein

BDNF belongs to the NGF family of neurotrophic growth factors, supporting neuron growth and survival. It binds to a low-affinity cell surface receptor, LNGFR, shared with other neurotrophins like NGF, NT-3, and NT-4. However, BDNF primarily exerts its...

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Human NT-4 Recombinant Protein

NT-4 is a neurotrophic factor sharing structural similarities with β-NGF, BDNF, and NT-3, all part of the cysteine-knot family of growth factors characterized by stable dimeric structures. It is expressed in various tissues such as the prostate,...

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Human NT-3 Recombinant Protein

NT-3, a neurotrophic factor, shares structural kinship with β-NGF, BDNF, and NT-4, all part of the cysteine-knot family of growth factors known for their stable dimeric structures. It's predominantly expressed by neurons in the central nervous...

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Human G-CSF Recombinant Protein

G-CSF serves as a hematopoietic growth factor, prompting the growth of dedicated progenitor cells into neutrophils and boosting the capabilities of mature end-cells. Its production is triggered by specific signals from various cells like macrophages,...

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Human GM-CSF Recombinant Protein

GM-CSF, a hematopoietic growth factor, plays a role in stimulating the development of neutrophils and macrophages while also supporting the proliferation and maturation of early erythroid, megakaryocytic, and eosinophilic progenitor cells. It's primarily...

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Human M-CSF Recombinant Protein

M-CSF, a potent hematopoietic factor, is generated by a variety of cells such as lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts, and osteoblasts. It serves as a crucial regulator of cellular proliferation, differentiation, and survival...

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Human IFN gamma Recombinant Protein

IFN-γ, an acid-labile interferon, is produced by CD4 and CD8 T lymphocytes as well as activated NK cells. Its receptors are widespread in immune cells, triggering an increase in class I MHC protein surface expression upon IFN-γ signaling...

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Human TNF alpha Recombinant Protein

TNF-α, a versatile pro-inflammatory cytokine, is produced by various cell types such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. It belongs to the TNF ligand family and interacts with two receptors, TNFR1 and...

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Human IL-21 Recombinant Protein

IL-21, a versatile cytokine, originates from CD4+ T cells upon encountering antigens. Its primary role involves enhancing the immune system's antigen-specific responses. IL-21 influences various immune cell activities: it fosters the transformation of T...

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Human IL-15 Recombinant Protein

IL-15 serves as an immunomodulatory cytokine that triggers the growth of T lymphocytes, sharing numerous traits with IL-2. Its primary effects are directed towards T cells, aiding in their development, longevity, and activation. Moreover, IL-15 plays a...

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Human IL-10 Recombinant Protein

IL-10, an immunosuppressive cytokine, is synthesized by various mammalian cell types like macrophages, monocytes, T cells, B cells, and keratinocytes. Its primary function is to dampen the expression of proinflammatory cytokines such as IL-1 and...

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