Human IL-5 Recombinant Protein

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SKU:
PC-H-IL5-100UG
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IL-5 functions as a growth factor in hematopoiesis, fostering the proliferation and activation of eosinophils. Its production primarily stems from mast cells, T cells, and eosinophils themselves. IL-5 plays a pivotal role in bolstering cell-mediated immunity against parasitic infections and specific tumors. Elevated IL-5 levels correlate with eosinophilia, a condition associated with the onset of asthma and other allergic disorders. Notably, both human and murine IL-5 exhibit cross-species reactivity. Recombinant Human IL-5 constitutes a 26.5 kDa disulfide-linked homodimeric protein, comprised of two 116 amino acid chains.

Product Specifications
 
Species Human
Expression System E. coli
Amino acid sequence
MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
Molecular weight 26.5 kDa
Class Recombinant
Type Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration <1 EU/µg
Activity
The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 10^6 units/mg.
Conjugate Unconjugated
Form Lyophilized
Contains
no preservative
Storage conditions -20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.