IL-7 is a hematopoietic growth factor with a key impact on early B and T cells. It originates from thymic stromal cells, spleen cells, and keratinocytes. In addition to its primary effects, IL-7 can collaborate with other factors like ConA and IL-2 to stimulate the proliferation of mature T cells. Interestingly, Human and murine IL-7 show cross-species reactivity.
Recombinant Human IL-7 is a 17.5 kDa protein comprising 153 amino acid residues.
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Product Specifications
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| Species | Human |
| Published species |
Hamster, Human, Mouse, Rabbit, Virus
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| Expression System | E. coli |
| Amino acid sequence |
MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
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| Molecular weight | 17.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity |
≥ 98% by SDS-PAGE gel and HPLC analyses.
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| Endotoxin concentration | <1 EU/µg |
| Activity |
Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
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| Conjugate | Unconjugated |
| Form | Lyophilized |
| Contains |
no preservative
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| Storage conditions | -20°C |
CAUTION
For Research Use Only. Not for use in diagnostic procedures.
