KGF, also known as FGF-7, belongs to the FGF family, which comprises 23 known members. This family of proteins plays a pivotal role in prenatal development, postnatal growth, and tissue regeneration by promoting cellular proliferation and differentiation. Specifically, KGF is a mitogen factor that targets epithelial cells and keratinocytes. It communicates its signals through FGFR 2b.
KGF contributes significantly to kidney and lung development, as well as to processes like angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein composed of 163 amino acid residues.
| Product Specifications | |
| Species | Human |
| Expression System | E.Coli |
| Amino Acid Sequence | CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT |
| Molecular Weight | 18.9 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin concentration | <1 EU/µg |
| Activity | Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml. |
| Conjugated | Unconjugated |
| Form | Lyophilized |
| Contains | No Preservative |
| Storage | -20°C |
CAUTION
For Research Use Only. Not for use in diagnostic procedures.
