Interleukins - Pacific Coast Biologics

Human IL-1 alpha Animal-Free Recombinant Protein

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Human IL-2 Animal-Free Recombinant Protein

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Human IL-3 Animal-Free Recombinant Protein

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Human IL-4 Animal-Free Recombinant Protein

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Human IL-5 Animal-Free Recombinant Protein

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Human IL-6 Animal-Free Recombinant Protein

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Human IL-7 Animal-Free Recombinant Protein

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Human IL-10 Animal-Free Recombinant Protein

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Human IL-11 Animal-Free Recombinant Protein

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Human IL-15 Animal-Free Recombinant Protein

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Human IL-17a Animal-Free Recombinant Protein

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Human IL-21 Animal-Free Recombinant Protein

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Human IL-1 alpha Animal-Free Recombinant Protein

IL-1α is a proinflammatory cytokine that is not secreted; it is produced by various cells like monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and share similar, if...

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Human IL-2 Animal-Free Recombinant Protein

IL-2 stands out as a potent immunoregulatory lymphokine generated by T cells following antigenic or mitogenic stimulation. Its signaling through IL-2R is critical for T cell proliferation and other vital immune response activities. IL-2 plays a pivotal...

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Human IL-3 Animal-Free Recombinant Protein

IL-3 acts as a crucial hematopoietic growth factor, supporting the survival, differentiation, and proliferation of specialized progenitor cells spanning various lineages such as megakaryocytes, granulocyte-macrophages, erythrocytes, eosinophils,...

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Human IL-4 Animal-Free Recombinant Protein

IL-4, a multifaceted cytokine, plays a crucial role in governing various T and B cell activities such as cell proliferation, survival, and gene expression. It is synthesized by mast cells, T cells, and bone marrow stromal cells. IL-4 specifically directs...

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Human IL-5 Animal-Free Recombinant Protein

IL-5 functions as a growth factor in hematopoiesis, fostering the proliferation and activation of eosinophils. Its production primarily stems from mast cells, T cells, and eosinophils themselves. IL-5 plays a pivotal role in bolstering cell-mediated...

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Human IL-6 Animal-Free Recombinant Protein

IL-6 is a multifaceted cytokine pivotal in host defense, orchestrating immune and inflammatory responses. It's generated by T cells, monocytes, fibroblasts, endothelial cells, and keratinocytes, showcasing a wide array of biological functions. IL-6...

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Human IL-7 Animal-Free Recombinant Protein

IL-7 is a hematopoietic growth factor with a key impact on early B and T cells. It originates from thymic stromal cells, spleen cells, and keratinocytes. In addition to its primary effects, IL-7 can collaborate with other factors like ConA and IL-2 to...

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Human IL-10 Animal-Free Recombinant Protein

IL-10, an immunosuppressive cytokine, is synthesized by various mammalian cell types like macrophages, monocytes, T cells, B cells, and keratinocytes. Its primary function is to dampen the expression of proinflammatory cytokines such as IL-1 and...

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Human IL-11 Animal-Free Recombinant Protein

IL-11, a versatile cytokine, is synthesized by stromal cells like fibroblasts, epithelial cells, and osteoclasts. Its expression spans various tissues such as the thymus, lung, bone, connective tissue, and central nervous system. IL-11 holds a crucial...

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Human IL-15 Animal-Free Recombinant Protein

IL-15 serves as an immunomodulatory cytokine that triggers the growth of T lymphocytes, sharing numerous traits with IL-2. Its primary effects are directed towards T cells, aiding in their development, longevity, and activation. Moreover, IL-15 plays a...

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Human IL-17a Animal-Free Recombinant Protein

Originally identified as IL-17 and now referred to as IL-17A, this protein is a homodimer consisting of two 136 amino acid chains. It is released by activated T-cells and acts on stromal cells, triggering the production of proinflammatory and...

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Human IL-21 Animal-Free Recombinant Protein

IL-21, a versatile cytokine, originates from CD4+ T cells upon encountering antigens. Its primary role involves enhancing the immune system's antigen-specific responses. IL-21 influences various immune cell activities: it fosters the transformation of T...

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